1-[2-[4-(Chloromethyl)phenoxy]ethyl]hexahydro-1H-azepine - Names and Identifiers
1-[2-[4-(Chloromethyl)phenoxy]ethyl]hexahydro-1H-azepine - Physico-chemical Properties
Molecular Formula | C15H22ClNO
|
Molar Mass | 267.79 |
Density | 1.075 |
Boling Point | 392.5±27.0 °C(Predicted) |
pKa | 8.80±0.20(Predicted) |
1-[2-[4-(Chloromethyl)phenoxy]ethyl]hexahydro-1H-azepine - Introduction
1-[2-[4-(Chloromethyl) phenyl] ethyl]hexahydro-1H-azepine is an organic compound, usually denoted by the abbreviation CMHEA (phenyl). The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless liquid or solid.
-Molecular formula: C14H22ClNO
-Molecular weight: 255.78g/mol
-Boiling point: About 238-241 ° C
-Density: about 1.097g/cm³
-Solubility: Slightly soluble in water, soluble in organic solvents such as methanol and ethanol.
Use:
1-[2-[4-(Chloromethyl) phenyl] ethyl]hexahydro-1H-azepine are commonly used as intermediates in organic synthesis and have two main application fields:
-Agricultural field: can be used for synthetic pesticides, herbicides, fungicides, etc.
-Pharmaceutical field: It can be used to synthesize anti-cancer drugs, anti-infective drugs, analgesic drugs, etc.
Method:
The preparation of 1-[2-[4-(Chloromethyl) phenyl] ethyl]hexahydro-1H-azepine is usually carried out by the following steps:
1. Chloroethanol reacts with chloromethylphenol under alkaline conditions to generate the corresponding chloromethylphenol ether estrone compound.
2. The compound is reacted with chloroethanol to generate 1-[2-[4-(Chloromethyl) phenyl] ethyl]hexahydro-1H-azepine.
Safety Information:
1-[2-[4-(chlorine methyl) phenyl] ethyl]hexahydro-1H-azepine is a chemical substance that should be handled and stored in a suitable laboratory environment. Here are some recommended safety considerations:
-Avoid contact with skin, eyes and respiratory tract.
-Wear appropriate personal protective equipment such as lab gloves, safety glasses and protective masks when operating.
-Operate in a well-ventilated place to avoid inhaling its vapor or dust.
-Comply with regulations for storage and handling of chemicals.
Please note that the above information is for reference only, and please follow the specific experimental conditions and safety regulations.
Last Update:2024-04-09 15:17:55